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11β-Prostaglandin E2

Names

[ CAS No. ]:
38310-90-6

[ Name ]:
11β-Prostaglandin E2

[Synonym ]:
l-7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
(5Z,11β,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5E,13E)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
5-Heptenoic acid, 7-[3-hydroxy-2- (3-hydroxy-1-octenyl)-5-oxocyclopentyl]-
5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-
7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
(5E)-7-{3-Hydroxy-2-[(1E)-3-hydroxy-1-octen-1-yl]-5-oxocyclopentyl}-5-heptenoic acid
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11β,13E,15S)-
prostaglandin-E2
5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-, l-
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5E,13E)-
7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid

Biological Activity

[Description]:

11β-Prostaglandin E2 (11β-Dinoprostone), a Prostanoid derivative, inhibits [3H]PGE2 binding to hypothalamic membranes in the rat with a Ki of 53.3 nM[1].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

[References]

[1]. F Dray, M Heaulme, et al. Prostaglandins of the E series inhibit release of noradrenaline in rat hypothalamus by a mechanism unrelated to classical alpha 2 adrenergic presynaptic inhibition. Neuropharmacology. 1984 Apr;23(4):457-62.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
530.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H32O5

[ Molecular Weight ]:
352.465

[ Flash Point ]:
288.5±26.6 °C

[ Exact Mass ]:
352.224976

[ PSA ]:
94.83000

[ LogP ]:
1.88

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.561

Related Compounds