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Caudatin

Names

[ CAS No. ]:
38395-02-7

[ Name ]:
Caudatin

[Synonym ]:
2-Pentenoic acid, 3,4-dimethyl-, (3β,12β,14β)-3,8,14,17-tetrahydroxy-20-oxopregn-5-en-12-yl ester, (2E)-
(3β,12β,14β)-3,8,14,17-Tetrahydroxy-20-oxopregn-5-en-12-yl (2E)-3,4-dimethyl-2-pentenoate

Biological Activity

[Description]:

Caudatin is a steroidal cmpound found in Cynanchum auriculatum, causes cell cycle arrest and induces apoptosis, with anti-cancer and antiangiogenic properties[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. Wang X, et al. Antiangiogenic properties of caudatin in vitro and in vivo by suppression of VEGF‑VEGFR2‑AKT/FAK signal axis. Mol Med Rep. 2017 Dec;16(6):8937-8943.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
617.9±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C28H42O7

[ Molecular Weight ]:
490.629

[ Flash Point ]:
197.5±25.0 °C

[ Exact Mass ]:
490.293060

[ PSA ]:
124.29000

[ LogP ]:
4.37

[ Vapour Pressure ]:
0.0±4.1 mmHg at 25°C

[ Index of Refraction ]:
1.584

[ Storage condition ]:
2-8C

Related Compounds