1,3-Propanediol-d2

Names

[ CAS No. ]:
38645-14-6

[ Name ]:
1,3-Propanediol-d2

[Synonym ]:
1,3-propanediol-2-d2
CH3CD2CH3
1,3-propanediol-2,2-d2
2,2-dideuteriopropane-1,3-diol
Propane-2,2-d2
propane-1,3-diol-2,2-d2
2,2-dideuterio-propane
2,2-Dideuterio-propan

Biological Activity

[Description]:

1,3-Propanediol-d2 is the deuterium labeled 1,3-Propanediol[1]. 1,3-Propanediol is produced in nature by the fermentation of glycerol in microorganism[2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. F. Barbirato, et al. Glycerol fermentation by a new 1,3-propanediol-producing microorganism:Enterobacter agglomerans. Applied Microbiology and Biotechnology volume 43, pages786-793(1995).

Chemical & Physical Properties

[ Molecular Formula ]:
C3H6D2O2

[ Molecular Weight ]:
78.10670

[ Exact Mass ]:
78.06500

[ PSA ]:
40.46000

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds