Eriodictyol-7-O-glucoside

Names

[ Name ]:
Eriodictyol-7-O-glucoside

[Synonym ]:
3',4',5,7-Tetrahydroxyflavanone-7-glucoside
ERIODICTYOL-7-GLUCOSIDE
(2S)-2-(3,4-Dihydroxyphényl)-5-hydroxy-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromén-4-one
pyracanthoside
eriodictyol-7-O-glucoside
(2S)-2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-3,4-dihydro-2H-chromen-7-yl β-D-glucopyranoside
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-, (2S)-
(2S)-2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromen-4-one
(2S)-2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromen-4-on
(2S)-2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-3,4-dihydro-2H-chromen-7-yl-β-D-glucopyranoside
(S)-2-(3,4-Dihydroxyphenyl)-7-(b-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one

Biological Activity

[Description]:

Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is a potent free radical scavenger. Eriodictyol-7-O-glucoside is also an Nrf2 activator, confers protection against Cisplatin-induced toxicity[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> Keap1-Nrf2

Research Areas >> Metabolic Disease

[Target]

Nrf2[1]

[References]

[1]. Hu Q, et, al. Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity. Food Chem Toxicol. 2012 Jun;50(6):1927-32.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
841.0±65.0 °C at 760 mmHg

[ Melting Point ]:
171-176ºC

[ Molecular Formula ]:
C₂₁H₂₂O₁₁

[ Molecular Weight ]:
450.393

[ Flash Point ]:
296.9±27.8 °C

[ Exact Mass ]:
450.116211

[ PSA ]:
186.37000

[ LogP ]:
0.22

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Index of Refraction ]:
1.713

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

Articles

Two new hepatoprotective stilbene glycosides from Acer mono leaves.

J. Nat. Prod. 68 , 101-3, (2005)

Two new stilbene glycosides, 5-O-methyl-(E)-resveratrol 3-O-beta-d-glucopyranoside (1) and 5-O-methyl-(E)-resveratrol 3-O-beta-D-apiofuranosyl-(1-->6)-beta-d-glucopyranoside (2), were isolated from th...

Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity

Food Chem. Toxicol. 50 , 1927-1932, (2012)

Graphical abstract Eriodictyol-7-O-glucoside was identified as a novel Nrf2 activator and the present study demonstrated the efficacy of the compound in battling cisplatin-induced toxicity. [Display o...