Phe-Ala

Names

[ Name ]:
Phe-Ala

[Synonym ]:
L-Alanine,N-L-phenylalanyl
Phe-ala
Phenylalanylalanine
L-Phenylalanyl-L-alanine
L-phenylalanine-L-alanine
L-Phe-L-Ala-OH
Phenylalanine-Alanine
L-Phe-L-Ala
H-PHE-ALA-OH
H-Phe-β-Ala-OH

Biological Activity

[Description]:

Phenylalanylalanine (H-Phe-Ala-OH) is a dipeptide composed of phenylalanine and alanine. Phenylalanylalanine is an incomplete breakdown product of protein digestion or protein catabolism[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Facchin G, et al. Experimental and theoretical studies of copper complexes with isomeric dipeptides as novel candidates against breast cancer. J Inorg Biochem. 2016;162:52‐61.

Chemical & Physical Properties

[ Density]:
1.222g/cm3

[ Boiling Point ]:
506ºC at 760mmHg

[ Melting Point ]:
241℃ (Decomposition)

[ Molecular Formula ]:
C₁₂H₁₆N₂O₃

[ Molecular Weight ]:
236.26700

[ Flash Point ]:
259.8ºC

[ Exact Mass ]:
236.11600

[ PSA ]:
92.42000

[ LogP ]:
1.23690

[ Index of Refraction ]:
1.565

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Alkali metal complexes of the dipeptides PheAla and AlaPhe: IRMPD spectroscopy.

ChemPhysChem 9 , 579-589, (2008)

Complexes of PheAla and AlaPhe with alkali metal ions Na(+) and K(+) are generated by electrospray ionization, isolated in the Fourier-transform ion cyclotron resonance (FT-ICR) ion trapping mass spec...

Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-beta3-hAla-NHMe and Ac-beta3-hAla-beta3-hPhe-NHMe.

J. Am. Chem. Soc. 130(14) , 4795-807, (2008)

The conformational preferences and infrared and ultraviolet spectral signatures of two model beta-peptides, Ac-beta3-hPhe-beta3-hAla-NHMe (1) and Ac-beta3-hAla-beta3-hPhe-NHMe (2), have been explored ...

A novel inhibitor of the mammalian peptide transporter PEPT1.

Biochemistry 40(14) , 4454-8, (2001)

This study was initiated to develop inhibitors of the intestinal H(+)/peptide symporter. We provide evidence that the dipeptide derivative Lys[Z(NO(2))]-Pro is an effective competitive inhibitor of ma...