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4H-Thieno[3,2-b]pyrrole-5-carboxylic acid

Names

[ CAS No. ]:
39793-31-2

[ Name ]:
4H-Thieno[3,2-b]pyrrole-5-carboxylic acid

[Synonym ]:
4H-Thieno[3,2-b]pyrrole-5-carboxylic acid

Biological Activity

[Description]:

DAO-IN-2 is a novel D-amino acid oxidase (DAO) inhibitor. DAO-IN-2 demonstrates moderate potency for DAO in vitro and ex vivo[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Tim Sparey, et, al. The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorg Med Chem Lett. 2008,18, 11.  

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
437.4±25.0 °C at 760 mmHg

[ Melting Point ]:
180ºC

[ Molecular Formula ]:
C7H5NO2S

[ Molecular Weight ]:
167.19

[ Flash Point ]:
218.3±23.2 °C

[ Exact Mass ]:
167.004105

[ PSA ]:
81.33000

[ LogP ]:
3.24

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.786

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds