Cassyfiline

Names

[ Name ]:
Cassyfiline

[Synonym ]:
(7aS)-4,11-Dimethoxy-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-10-ol
5H-1,3-Benzodioxolo[6,5,4-de]benzo[g]quinolin-10-ol, 6,7,7a,8-tetrahydro-4,11-dimethoxy-, (7aS)-

Biological Activity

[Description]:

Cassyfiline (Cassythine) is an aporphine alkaloid. Cassyfiline has potent vasorelaxing effects on precontracted rat aortic preparations with an IC50 of 0.09 μM[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Tung-Hu Tsai, et al. Vasorelaxing alkaloids and flavonoids from Cassytha filiformis. J Nat Prod. 2008 Feb;71(2):289-91.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
552.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₁₉NO₅

[ Molecular Weight ]:
341.36

[ Flash Point ]:
287.8±30.1 °C

[ Exact Mass ]:
341.126312

[ PSA ]:
69.18000

[ LogP ]:
2.49

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.640

Safety Information

[ Hazard Codes ]:
Xi