Thionicotinamide adenine dinucleotide

Names

[ Name ]:
Thionicotinamide adenine dinucleotide

[Synonym ]:
adenosine 5'-(trihydrogen diphosphate)
adenosine 5'-(trihydrogen diphosphate),5'->5'-ester with 3-(aminothioxomethyl)-1-
thio-nicotinamide adenine dinucleotide
Diphosphorsaeure-1-adenosin-5'-ylester-2-[(1R)-1-(3-thiocarbamoyl-pyridinio)-D-1,4-anhydro-ribit-5-ylester]-betain
3-Thionicotinamide adenine dinucleotide
Thionicotinamide adenine dinucleotide
THIO-NAD
Thionicotinamide-NAD
Thionicotinamide-DPN
MFCD00079609
Thionicotinamide-DPN oxidized form
EINECS 223-828-6

Biological Activity

[Description]:

Thionicotinamide adenine dinucleotide (Thio-NAD) is a dinucleotide substrate[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. William E Karsten, et al.Tartrate dehydrogenase catalyzes the stepwise oxidative decarboxylation of D-malate with both NAD and thio-NAD. Biochemistry. 2002 Oct 8;41(40):12193-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₇N₇O₁₃P₂S

[ Molecular Weight ]:
679.491

[ Exact Mass ]:
679.086304

[ PSA ]:
355.73000

[ LogP ]:
-8.33

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

DownStream

Articles

Self-inactivation of an erythrocyte NAD glycohydrolase.

Mol. Cell Biochem. 31(1) , 49-56, (1980)

NAD glycohydrolase activity was studied using bovine erythrocytes, erythrocyte ghosts and partially purified enzyme preparations. During catalysis the enzyme becomes irreversibly inactivated in a proc...

Kinetic study of the enzymatic cycling reaction conducted with 3alpha-hydroxysteroid dehydrogenase in the presence of excessive thio-NAD(+) and NADH.

Anal. Biochem. 332(1) , 84-9, (2004)

We have established a simple kinetic model applicable to the enzyme cycling reaction for the determination of 3alpha-hydroxysteroids. This reaction was conducted under the reversible catalytic functio...

Tartrate dehydrogenase catalyzes the stepwise oxidative decarboxylation of D-malate with both NAD and thio-NAD.

Biochemistry 41(40) , 12193-9, (2002)

Tartrate dehydrogenase catalyzes the divalent metal ion- and NAD-dependent oxidative decarboxylation of D-malate to yield CO(2), pyruvate, and NADH. The enzyme also catalyzes the metal ion-dependent o...