2'-Hydroxy-2-methoxychalcone

Names

[ Name ]:
2'-Hydroxy-2-methoxychalcone

[Synonym ]:
(2E)-1-(2-hydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one
1-(2-HYDROXYPHENYL)-3-(2-METHOXYPHENYL)PROP-2-EN-1-ONE
(E)-1-(2-hydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one
[E]-3-(o-methoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one
2'-FORMYL-[1,1'-BIPHENYL]-3-CARBOXYLIC ACID
2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(2-methoxyphenyl)-

Biological Activity

[Description]:

2'-Hydroxy-2-methoxychalcone (compound 3b) is a synthetic chalcone, with antimicrobial activity[1].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Witold Gładkowski, et al. Synthesis and Antimicrobial Activity of Methoxy- Substituted γ-Oxa-ε-lactones Derived from Flavanones. Molecules. 2019 Nov 16;24(22):4151.

Chemical & Physical Properties

[ Density]:
1.197g/cm3

[ Boiling Point ]:
430.6ºC at 760 mmHg

[ Melting Point ]:
112-113ºC

[ Molecular Formula ]:
C₁₆H₁₄O₃

[ Molecular Weight ]:
254.28100

[ Flash Point ]:
161.1ºC

[ Exact Mass ]:
254.09400

[ PSA ]:
46.53000

[ LogP ]:
3.29690

[ Index of Refraction ]:
1.631

Safety Information

[ Hazard Codes ]:
Xn

[ HS Code ]:
2914509090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

2'-​Hydroxy-​2-​methoxychalcone