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Pedunculoside

Names

[ CAS No. ]:
42719-32-4

[ Name ]:
Pedunculoside

[Synonym ]:
β-D-Glucopyranose, 1-O-[(3β)-3,19,23-trihydroxy-28-oxours-12-en-28-yl]-
Pedunculoside
1-O-[(3Beta)-3,19,23-Trihydroxy-28-oxours-12-en-28-yl]-Beta-D-glucopyranose
1-O-[(3β)-3,19,23-Trihydroxy-28-oxours-12-en-28-yl]-β-D-glucopyranose

Biological Activity

[Description]:

Pedunculoside is a main bioactive component isolated from Jiubiying. Pedunculoside exerts lipid-lowering effects partly through the regulation of lipogenesis and fatty acid β-oxidation[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Fatty Acid Synthase (FAS)
Research Areas >> Metabolic Disease

[In Vitro]

Pedunculoside is a triterpene saponin extracted from Ilex rotunda Thunb. Pedunculoside regulates PPAR-γ, CCAAT/Enhancer-binding Protein α(C/EBPα)、and SREBP-1 expression as well as inhibited phosphorylation of AMPK in MDI (methylisobutylxanthine, dexamethasone, insulin) induced-3T3L1 cells[1].

[References]

[1]. Liu C, et al. Pedunculoside, a novel triterpene saponin extracted from Ilex rotunda, ameliorates high-fat diet induced hyperlipidemia in rats. Biomed Pharmacother. 2018 May;101:608-616.

Chemical & Physical Properties

[ Density]:
1.31

[ Boiling Point ]:
760.1±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C36H58O10

[ Molecular Weight ]:
650.840

[ Flash Point ]:
230.3±26.4 °C

[ Exact Mass ]:
650.403015

[ PSA ]:
177.14000

[ LogP ]:
5.01

[ Vapour Pressure ]:
0.0±5.8 mmHg at 25°C

[ Index of Refraction ]:
1.606

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds