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Desfluoro-atorvastatin

Names

[ CAS No. ]:
433289-84-0

[ Name ]:
Desfluoro-atorvastatin

[Synonym ]:
unii-831wx29c91
Atorvastatin Impurity 26

Biological Activity

[Description]:

Desfluoro-atorvastatin is an impurity of Atorvastatin[1]. Atorvastatin is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, has the ability to effectively decrease blood lipids[2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology
Research Areas >> Metabolic Disease

[References]

[1]. Ertürk S, et al. An HPLC method for the determination of atorvastatin and its impurities in bulk drug and tablets. J Pharm Biomed Anal. 2003 Dec 4;33(5):1017-23.

[2]. Santodomingo-Garzón T, et al. Atorvastatin inhibits inflammatory hypernociception. Br J Pharmacol. 2006 Sep;149(1):14-22.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H36N2O5

[ Molecular Weight ]:
540.64900

[ Exact Mass ]:
540.26200

[ PSA ]:
115.28000

[ LogP ]:
6.55850

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds