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acetyl oleanolic acid

Names

[ CAS No. ]:
4339-72-4

[ Name ]:
acetyl oleanolic acid

[Synonym ]:
Olean-12-en-28-oic acid, 3-(acetyloxy)-, (3β)-
3-O-acetyloleanolic acid
acetyl oleanolic acid
(3β)-3-Acetoxyolean-12-en-28-oic acid
Oleanolic acid 3-acetate
Olean-12-en-28-oic acid, 3β-hydroxy-, acetate

Biological Activity

[Description]:

3-O-Acetyloleanolic acid (3AOA), an oleanolic acid derivative isolated from the seeds of Vigna sinensis K., induces in cancer and also exhibits anti-angiogenesis activity[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[Target]

Apoptosis[1].


[References]

[1]. Yoo KH, et al. 3-O-acetyloleanolic acid induces apoptosis in human colon carcinoma HCT-116 cells. Phytother Res. 2012 Oct;26(10):1541-6.

[2]. Hwang-Bo J, et al. 3-O-Acetyloleanolic acid inhibits VEGF-A-induced lymphangiogenesis and lymph node metastasis in an oral cancer sentinel lymph node animal model. BMC Cancer. 2018 Jul 5;18(1):714.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
564.4±50.0 °C at 760 mmHg

[ Melting Point ]:
265-268 ℃

[ Molecular Formula ]:
C32H50O4

[ Molecular Weight ]:
498.737

[ Flash Point ]:
170.4±23.6 °C

[ Exact Mass ]:
498.370911

[ PSA ]:
63.60000

[ LogP ]:
9.95

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Index of Refraction ]:
1.545

Safety Information

[ Hazard Codes ]:
Xi

Precursor & DownStream

Precursor

DownStream

Related Compounds