4-Hydroxyatomoxetine
Names
[ CAS No. ]:
435293-66-6
[ Name ]:
4-Hydroxyatomoxetine
[Synonym ]:
UNII-6T2XYC0A9R
4`-Hydroxy Atomoxetine
Biological Activity
[Description]:
4-Hydroxyatomoxetine is an active metabolite of Atomoxetine. 4-Hydroxyatomoxetine is metabolized by the enzyme cytochrome P450 2D6 (CYP2D6). Atomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5 nM, 77 nM and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively)[1][2].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C17H21NO2
[ Molecular Weight ]:
271.35400
[ Exact Mass ]:
271.15700
[ PSA ]:
41.49000
[ LogP ]:
3.82110