Epipodophyllotoxin
Names
[ CAS No. ]:
4375-07-9
[ Name ]:
Epipodophyllotoxin
[Synonym ]:
Sunphenon EGC
Epipodophyllotoxin
EPIGALLOCATECHIN
Teacatechin II
epi
Galloepicatechin
epigallocatechol
Greenteacatechins
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.37g/cm3
[ Boiling Point ]:
597.9ºC at 760 mmHg
[ Melting Point ]:
160.3 °C
[ Molecular Formula ]:
C22H22O8
[ Molecular Weight ]:
414.40500
[ Flash Point ]:
210.2ºC
[ Exact Mass ]:
414.13100
[ PSA ]:
92.68000
[ LogP ]:
2.40920
[ Index of Refraction ]:
1.605
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LV2520000
- CAS REGISTRY NUMBER :
- 4375-07-9
- BEILSTEIN REFERENCE NO. :
- 0099162
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C22-H22-O8
- MOLECULAR WEIGHT :
- 414.44
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 135 mg/kg
- SEX/DURATION :
- female 25 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - menstrual cycle changes or disorders
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 20 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 48,512,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5374 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 214 (estimated) No. of Female Employees: 214 (estimated)