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ITK inhibitor

Names

[ CAS No. ]:
439574-61-5

[ Name ]:
ITK inhibitor

[Synonym ]:
ITK inhibitor
HMS3265G21
HMS3265G22
HMS3265H21
Benzamide, N-[5-[[5-[(4-acetyl-1-piperazinyl)carbonyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-4-[[(1,2-dimethylpropyl)amino]methyl]-
HMS3265H22
N-[5-({5-[(4-Acetyl-1-piperazinyl)carbonyl]-4-methoxy-2-methylphenyl}sulfanyl)-1,3-thiazol-2-yl]-4-{[(3-methyl-2-butanyl)amino]methyl}benzamide

Biological Activity

[Description]:

ITK inhibitor is a potent ITK inhibitor.

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Itk
Research Areas >> Inflammation/Immunology

[References]

[1]. Barrish, Joel C.; Das, Jagabandhu; Kanner, Steven B.; Liu, Chunjian; Spergel, Steven H.; Witayk, John; Doweyko, Arthur M. P.; Furch, Joseph A. Preparation of thiazolyl inhibitors of Tec family tyrosine kinases. PCT Int. Appl.(2002),149 pp.


[Related Small Molecules]

BMS-509744 | PRN694 | Vecabrutinib | GNE-4997

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C31H39N5O4S2

[ Molecular Weight ]:
609.802

[ Exact Mass ]:
609.244324

[ PSA ]:
157.41000

[ LogP ]:
4.20

[ Index of Refraction ]:
1.640

Related Compounds