6-Azauracil

Names

[ CAS No. ]:
461-89-2

[ Name ]:
6-Azauracil

[Synonym ]:
USAF cb-30
1,2,4-Triazine-3,5-dione
EINECS 207-318-0
1,2,4-Triazine-3,5(2H,4H)-dione
3,5-dihydroxy-1,2,4-triazine
1,2,4-triazine-3,5-diol
6-aza uracile
Azauracil
2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione
ipo3834
1,2,4-Triazine-3,5(2H,4H)-dione,3,5-Dihydroxy-1,2,4-triazine,6-Aza-2,4-dihydroxypyrimidine
AZAURACIL,6
6-AZAURAZIL
3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine
AZU
6-Azauracil
MFCD00006456

Biological Activity

[Description]:

1,2,4-Triazine-3,5(2H,4H)-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
503.4ºC at 760 mmHg

[ Melting Point ]:
274-275 °C(lit.)

[ Molecular Formula ]:
C₃H₃N₃O₂

[ Molecular Weight ]:
113.07

[ Flash Point ]:
258.3ºC

[ Exact Mass ]:
113.022530

[ PSA ]:
78.61000

[ LogP ]:
-0.59

[ Index of Refraction ]:
1.749

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XY7700000

CHEMICAL NAME :: 1,2,4-Triazine-3,5(2H,4H)-dione

CAS REGISTRY NUMBER :: 461-89-2

LAST UPDATED :: 199709

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C3-H3-N3-O2

MOLECULAR WEIGHT :: 113.09

WISWESSER LINE NOTATION :: T6NMVMVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2076 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 39 gm/kg/1Y-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - testicular tumors

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Microorganism - not otherwise specified

DOSE/DURATION :: 80 mg/L

REFERENCE :: ZBPIA9 Zentralblatt fuer Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene, Abteilung II. Naturwissenschaftliche: Allgemeine, Landwirtschaftliche und Technische Mikrobiologie. (Jena, Ger. Dem. Rep.) V.107-132, 1952-77. Volume(issue)/page/year: 130,1,1975 *** REVIEWS *** TOXICOLOGY REVIEW 32XPAD "Teratology," Berry, C.L., and D.E. Poswillo, eds., New York, Springer, 1975 Volume(issue)/page/year: -,49,1975

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R25;R36/37/38;R63

[ Safety Phrases ]:
S26-S36-S45-S38-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
XY7700000

[ HS Code ]:
29336980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 29336980

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