L-Aspartic acid,N-benzoyl-

Names

[ Name ]:
L-Aspartic acid,N-benzoyl-

[Synonym ]:
N-Benzoyl-4-nitro-L-phenylalanin
N-Benzoyl-L-asparaginsaeure
N-benzoyl-4-nitro-L-phenylalanine
N-benzoylaspartate
N-Benzoyl-L-aspartic acid
L-N-benzoylaspartic acid
N-Benzoyl-p-nitro-L-phenylalanin

Biological Activity

[Description]:

N-benzoyl-L-aspartic acid, a major metabolite of benzyl glucosinolate, can be used for modification of peptides or proteins[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

N-benzoyl-L-aspartic acid resists racemisation by aqueous acetic anhydride and evidence is adduced to show that they form internal anhydrides rather than oxazolones under these conditions[2].

[References]

[1]. Friedrichs J, et, al. Novel glucosinolate metabolism in larvae of the leaf beetle Phaedon cochleariae. Insect Biochem Mol Biol. 2020 Sep;124:103431.

[2]. BARKER CC, et, al. The Dehydration and Racemisation of N-Acyl-L-aspartic Acids by Acetic Anhydride. Journal of the Chemical Society. 1953.

Chemical & Physical Properties

[ Density]:
1.404g/cm3

[ Boiling Point ]:
502ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₁NO₅

[ Molecular Weight ]:
237.20900

[ Flash Point ]:
257.4ºC

[ Exact Mass ]:
237.06400

[ PSA ]:
103.70000

[ LogP ]:
0.73520

[ Index of Refraction ]:
1.588

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CI9100000

CHEMICAL NAME :: L-Aspartic acid, N-benzoyl-

CAS REGISTRY NUMBER :: 4631-12-3

BEILSTEIN REFERENCE NO. :: 2507411

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H11-N-O5

MOLECULAR WEIGHT :: 237.23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1740 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 25,569,1991

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%