Rehmannic acid
Names
[ CAS No. ]:
467-81-2
[ Name ]:
Rehmannic acid
[Synonym ]:
(22β)-22-{[(2Z)-2-Methyl-2-butenoyl]oxy}-3-oxoolean-12-en-28-oic acid
Olean-12-en-28-oic acid, 22-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]-3-oxo-, (22β)-
Biological Activity
[Description]:
Rehmannic acid (lantadene A) is a compound isolated from Lantana camara. Rehmannic acid shows considerable in vitro antioxidant, free radical scavenging capacity activities in a dose dependant manner. Rehmannic acid is a promising candidate for use as an antioxidant and hepatoprotective agent[1][2].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
626.3±55.0 °C at 760 mmHg
[ Molecular Formula ]:
C35H52O5
[ Molecular Weight ]:
552.784
[ Flash Point ]:
187.9±25.0 °C
[ Exact Mass ]:
552.381470
[ PSA ]:
80.67000
[ LogP ]:
9.56
[ Vapour Pressure ]:
0.0±3.9 mmHg at 25°C
[ Index of Refraction ]:
1.552
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RK0252000
- CHEMICAL NAME :
- Olean-12-en-28-oic acid, 22-beta-hydroxy-3-oxo-, 2-methylcrotonate, (Z)-
- CAS REGISTRY NUMBER :
- 467-81-2
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C35-H52-O5
- MOLECULAR WEIGHT :
- 552.87
- WISWESSER LINE NOTATION :
- L F6 E6 B666 TV DUTJ A1 H1 H1 JOVY1&U2 KVQ N1 O1 S1 S1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - domestic
- DOSE/DURATION :
- 65 mg/kg
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Gastrointestinal - decreased motility or constipation Liver - jaundice, other or unclassified
- REFERENCE :
- AUVJA2 Australian Veterinary Journal. (Australian Veterinary Assoc., Executive Director, 134-136 Hampden Road, Artarmon, N.S.W., Australia) V.2- 1927- Volume(issue)/page/year: 53,230,1977
Safety Information
[ Hazard Codes ]:
Xi