2-Biphenylylboronic acid

Names

[ Name ]:
2-Biphenylylboronic acid

[Synonym ]:
(2-phenylphenyl)boronic acid
MFCD00136929
Biphenyl-2-boronic acid
2-Biphenylboronicacid
2-Biphenylboronic Acid
Biphenyl-2-ylboronic acid
1,1′-biphenyl-2-yl-boronic acid
Boronic acid, B-[1,1'-biphenyl]-2-yl-
2-Biphenylylboronic acid
[1,1'-biphenyl]-2-ylboronic acid

Biological Activity

[Description]:

2-Biphenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

2-Biphenylboronic acid 是一种底物，用于钯催化的与乙酸苄酯的交叉偶联，提供二芳基甲烷。它是参与与芳基卤化物、二溴乙烯基前体、烯基甲苯磺酸酯和甲磺酸酯以及喹啉羧酸酯的 Suzuki-Miyaura 交叉偶联反应的反应物。它参与用于合成手性四氢萘的分子内 Friedel-Crafts 烷基化、羟基化为酚类以及与炔烃的氧化偶联。

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
404.0±38.0 °C at 760 mmHg

[ Melting Point ]:
167-172 °C(lit.)

[ Molecular Formula ]:
C₁₂H₁₁BO₂

[ Molecular Weight ]:
198.03

[ Flash Point ]:
198.1±26.8 °C

[ Exact Mass ]:
198.085205

[ PSA ]:
40.46000

[ LogP ]:
3.35

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.610

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
C: Corrosive;Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29310095

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

Cross-coupling of benzylic acetates with arylboronic acids: one-pot transformation of benzylic alcohols to diarylmethanes.

Chem. Commun. (Camb.) , 5899, (2005)

Benzylic acetates reacted with arylboronic acids in the presence of a DPEphos-[Pd(eta3-C3H5)Cl]2 catalyst when tert-amyl alcohol was used as a solvent, and the catalytic cross-couplings produced diary...