5'-IMPdisodium salt

Names

[ Name ]:
5'-IMPdisodium salt

[Synonym ]:
Inosine-5'-monophosphoric acid disodium salt
IMP SODIUM SALT
INOSINIC ACID
5'-IMP-Na
Sodium Inosine 5'-Phosphate
IMP,NA2
5'-Inosinic Acid Disodium Salt Hydrate
9H-purin-6-ol, 9-(5-O-phosphono-β-D-ribofuranosyl)-, sodium salt (1:2)
Inosine-5'-monophosphate disodium
disodiumimp
Disodium 5-Inosinate
EINECS 225-146-4
5'-IMP 2Na Hydrate
5'-Inosinic acid, sodium salt (1:2)
Inosine 5'-Monophosphate DisodiuM Salt Hydrate
Inosine 5′-monophosphate disodium salt
Disodium Inosinate Hydrate
Disodium 9-(5-O-phosphonato-β-D-ribofuranosyl)-9H-purin-6-ol
MFCD00036201
Disodium 5'-O-phosphonatoinosine
5'-IMP 2Na
IMP 2NA
Disodium inosine 5'-monophosphate
inosine-5'-monophosphate sodium salt
inosine 5'-phosphate disodium salt
Sodium 5'-inosinate
sodiuminosinate
IMP-5
FEMA 3669
Inosic Acid Disodium Salt Hydrate
Disodium 5’-Inosinate

Biological Activity

[Description]:

Disodium 5'-inosinate, obtained from bacterial fermentation of sugars, is as a food additive and often found in a variety of other snacks.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
2.31g/cm3

[ Boiling Point ]:
851.4ºC at 760 mmHg

[ Melting Point ]:
175 °C

[ Molecular Formula ]:
C₁₀H₁₁N₄Na₂O₈P

[ Molecular Weight ]:
392.170

[ Flash Point ]:
468.7ºC

[ Exact Mass ]:
392.010986

[ PSA ]:
195.49000

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NM7519500

CHEMICAL NAME :: 5'-Inosinic acid, disodium salt

CAS REGISTRY NUMBER :: 4691-65-0

LAST UPDATED :: 199701

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C10-H11-N4-O8-P.2Na

MOLECULAR WEIGHT :: 392.20

WISWESSER LINE NOTATION :: T56 BN DN FVO INJ B- BT5OTJ CQ DQ E1OPWO &-NA- 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15900 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4850 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3900 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2730 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5480 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 693 gm/kg/26W-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in spleen weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 250 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 500 mg/kg

SEX/DURATION :: female 13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Fibroblast

DOSE/DURATION :: 1 gm/L

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,623,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1104 No. of Facilities: 213 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 3527 (estimated) No. of Female Employees: 1444 (estimated)

Safety Information

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R23/24/25;R36/37/38

[ Safety Phrases ]:
S22-S26-S36-S45

[ WGK Germany ]:
3

[ RTECS ]:
NM7519500

[ Packaging Group ]:
II; III

[ HS Code ]:
2103909000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2103909000