Steviol

Names

[ CAS No. ]:
471-80-7

[ Name ]:
Steviol

[Synonym ]:
steviol
(5β,8α,9β,10α,13α)-13-Hydroxykaur-16-en-18-oic acid
Stevioside
Hydroxydehydrostevic acid
Steviol hydrate

Biological Activity

[Description]:

Steviol is a major metabolite of the sweetening compound stevioside. Steviol slows renal cyst growth by reducing AQP2 expression and promoting AQP2 degradation[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Noitem R, et al. Steviol slows renal cyst growth by reducing AQP2 expression and promoting AQP2 degradation. Biomed Pharmacother. 2018 May;101:754-762.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
464.5±45.0 °C at 760 mmHg

[ Melting Point ]:
215°

[ Molecular Formula ]:
C₂₀H₃₀O₃

[ Molecular Weight ]:
318.450

[ Flash Point ]:
248.8±25.2 °C

[ Exact Mass ]:
318.219482

[ PSA ]:
57.53000

[ LogP ]:
4.44

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.569

[ Storage condition ]:
2-8C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NZ8176000

CHEMICAL NAME :: Kaur-16-en-18-oic acid, 13-hydroxy-

CAS REGISTRY NUMBER :: 471-80-7

LAST UPDATED :: 199410

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H30-O3

MOLECULAR WEIGHT :: 318.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 gm/L

REFERENCE :: PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 82,2478,1985

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
NZ8176000

Precursor & DownStream

Precursor

DownStream

Articles

High-performance thin-layer chromatography analysis of steviol glycosides in Stevia formulations and sugar-free food products, and benchmarking with (ultra) high-performance liquid chromatography.

J. Chromatogr. A. 1350 , 102-11, (2014)

A high-performance TLC (HPTLC) method was newly developed and validated for analysis of 7 steviol glycosides in 6 different types of food and Stevia formulations. After a minimized one-step sample pre...

Preparation and chromatographic evaluation of a newly designed steviol glycoside modified-silica stationary phase in hydrophilic interaction liquid chromatography and reversed phase liquid chromatography.

J. Chromatogr. A. 1388 , 110-8, (2015)

A diterpene glycoside compound, rebaudioside A (commonly abbreviated as RA), was immobilized onto porous silica surface through "thiol-ene" click chemistry strategy. The successful immobilization of t...

Determination of eight artificial sweeteners and common Stevia rebaudiana glycosides in non-alcoholic and alcoholic beverages by reversed-phase liquid chromatography coupled with tandem mass spectrometry.

Anal. Bioanal. Chem 407(5) , 1505-12, (2015)

The method for the determination of acesulfame-K, saccharine, cyclamate, aspartame, sucralose, alitame, neohesperidin dihydrochalcone, neotame and five common steviol glycosides (rebaudioside A, rebau...