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C6 NBD Lactosylceramide (d18:1/6:0)

Names

[ CAS No. ]:
474943-04-9

[ Name ]:
C6 NBD Lactosylceramide (d18:1/6:0)

[Synonym ]:
N-[(2S,3S,4E)-1-{[4-O-(β-D-Galactopyranosyl)-β-D-glucopyranosyl]oxy}-3-hydroxy-4-octadecen-2-yl]-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanamide
Hexanamide, N-[(1S,2S,3E)-1-[[(4-O-β-D-galactopyranosyl-β-D-glucopyranosyl)oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-

Biological Activity

[Description]:

C6 NBD Lactosylceramide is a derivative of lactosylceramides, and can be used in lactosylceramide synthase assay as a fluorescent acceptor substrate. C6 NBD Lactosylceramide can also be used in cancer research[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Samy A F Morad, et al. Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer. Biochem Pharmacol. 2017 Apr 15;130:21-33.

[2]. J W Kok, et al. Sorting of sphingolipids in the endocytic pathway of HT29 cells. J Cell Biol. 1991 Jul;114(2):231-9.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C42H69N5O16

[ Molecular Weight ]:
900.021

[ Exact Mass ]:
899.473938

[ LogP ]:
6.10

[ Index of Refraction ]:
1.605

Related Compounds