ZSTK474
Names
[ CAS No. ]:
475110-96-4
[ Name ]:
ZSTK474
[Synonym ]:
2wxl
1H-Benzimidazole, 2-(difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-
ZSTK474
2-(Difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole
ZSTK-474,ZST K474
ZSTK-474
TCMDC-137004
S1072_Selleck
2-(Difluoromethyl)-1-[4,6-di(morpholin-4-yl)-1,3,5-triazin-2-yl]-1H-benzimidazole
4,4'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine
Biological Activity
[Description]:
[Related Catalog]:
[Target]
PI3Kα:16 nM (IC50)
PI3Kβ:44 nM (IC50)
PI3Kδ:4.6 nM (IC50)
PI3Kγ:49 nM (IC50)
Autophagy
[In Vitro]
[In Vivo]
[Kinase Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
640.3±65.0 °C at 760 mmHg
[ Molecular Formula ]:
C19H21F2N7O2
[ Molecular Weight ]:
417.413
[ Flash Point ]:
341.0±34.3 °C
[ Exact Mass ]:
417.172485
[ PSA ]:
81.43000
[ LogP ]:
-0.21
[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C
[ Index of Refraction ]:
1.711
[ Storage condition ]:
-20°C
Safety Information
[ HS Code ]:
2934999090
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%