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Benzamide,N-acetyl-2-hydroxy-

Names

[ CAS No. ]:
487-48-9

[ Name ]:
Benzamide,N-acetyl-2-hydroxy-

[Synonym ]:
Ethrisin
N-Salicoyl-acetamid
Actylamide
Arthrisin
N-Acetyl-salicylamid
salacetamide
Salicyl
L-749
Nacemide
Rixamone
Labazyl
Acetyl-salicyloyl-amin
acetyl-salicyloyl-amine

Biological Activity

[Description]:

Salacetamide (N-Acetylsalicylamide) is the stable isomer of O-Acetylsalicylamide, is a product for proteomics research[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. A.J.Gordon. Acetylsalicylamide o- to N-acetyl migration. Tetrahedron. 23(2). 1967:863-870.

Chemical & Physical Properties

[ Density]:
1.263g/cm3

[ Boiling Point ]:
375.4ºC at 760mmHg

[ Melting Point ]:
148°

[ Molecular Formula ]:
C9H9NO3

[ Molecular Weight ]:
179.17300

[ Flash Point ]:
180.9ºC

[ Exact Mass ]:
179.05800

[ PSA ]:
66.40000

[ LogP ]:
1.05940

[ Vapour Pressure ]:
3.6E-06mmHg at 25°C

[ Index of Refraction ]:
1.568

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VN6650000
CHEMICAL NAME :
Salicylamide, N-acetyl-
CAS REGISTRY NUMBER :
487-48-9
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H9-N-O3
MOLECULAR WEIGHT :
179.19
WISWESSER LINE NOTATION :
QR BVMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 89,205,1947
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2440378

Synthetic Route

Precursor & DownStream


Related Compounds