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Gaultherin

Names

[ CAS No. ]:
490-67-5

[ Name ]:
Gaultherin

[Synonym ]:
Methyl Salicylate-2-primeveroside
MONOTROPITOSIDE
Methyl Salicylate-2-glucoxyloside
2-[(6-O-b-D-Xylopyranosyl-b-D-glucopyranosyl)oxy]benzoic Acid Methyl Ester
methyl 2-[(6-o-pentopyranosylhexopyranosyl)oxy]benzoate
Gaultherin
Methyl 2-{[6-O-(β-D-xylopyranosyl)-β-D-glucopyranosyl]oxy}benzoate
Monotropitin
Benzoic acid, 2-[(6-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy]-, methyl ester
methyl 2-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-[[(2R,3S,4R,5S)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxybenzoate

Biological Activity

[Description]:

Gaultherin, a natural salicylate derivative, is isolated from Gaultheria yunnanensis. Gaultherin is a non-steroidal anti-inflammatory drug (NSAID). Gaultherin has analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to Aspirin[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Zhang B, et, al. Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug. Eur J Pharmacol. 2006 Jan 13;530(1-2):166-71.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
709.0±60.0 °C at 760 mmHg

[ Melting Point ]:
249.2ºC

[ Molecular Formula ]:
C19H26O12

[ Molecular Weight ]:
446.402

[ Flash Point ]:
249.2±26.4 °C

[ Exact Mass ]:
446.142426

[ PSA ]:
184.60000

[ LogP ]:
0.25

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.633

Precursor & DownStream

Precursor

DownStream

Related Compounds