CYP4A11/CYP4F2-IN-1

Names

[ Name ]:
CYP4A11/CYP4F2-IN-1

Biological Activity

[Description]:

CYP4A11/CYP4F2-IN-1 is a potent dual inhibitor of cytochrome P450 (CYP) 4A11 and CYP4F2, with IC50s of 19 nM and 17 nM, respectively. CYP4A11/CYP4F2-IN-1 has potential for the research of renal diseases[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450

Research Areas >> Metabolic Disease

[Target]

CYP4A11:19 nM (IC50)

CYP4F2:17 nM (IC50)

[In Vitro]

CYP4A11/CYP4F2-IN-1 (compound 2) inhibits 20-Hydroxyeicosatetraenoic acid (20-HETE) production from arachidonic acid in human renal microsomes, with an IC50 of 4.2 nM[1].

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₅N₃OS

[ Molecular Weight ]:
285.36

CYP4A11/CYP4F2-IN-1

Names

Biological Activity

Chemical & Physical Properties

Related Compounds