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Isoeuphorbetin

Names

[ CAS No. ]:
50886-61-8

[ Name ]:
Isoeuphorbetin

[Synonym ]:
Isoeuphorbetin
6,7,6',7'-Tetrahydroxy-[5,8']bichromenyl-2,2'-dione

Biological Activity

[Description]:

Isoeuphorbetin, a dimeric coumarin isolated from Viola philippica, is a potent HCV protease inhibitor with an IC50 of 3.63 µg/mL[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Metabolic Enzyme/Protease >> HCV Protease

[Target]

IC50: 3.63 µg/mL (HCV protease)[1]


[References]

[1]. Ya-Li Wang, et al. Lignans, flavonoids and coumarins from Viola philippica and their α-glucosidase and HCV protease inhibitory activities. Nat Prod Res. 2019 Jun;33(11):1550-1555.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H10O8

[ Molecular Weight ]:
354.26700

[ Exact Mass ]:
354.03800

[ PSA ]:
141.34000

[ LogP ]:
2.38880

Related Compounds