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Ertumaxomab

Names

[ CAS No. ]:
509077-99-0

[ Name ]:
Ertumaxomab

Biological Activity

[Description]:

Ertumaxomab (Anti-Human CD22 Recombinant Antibody) is a bispecific antibody targeting HER2/neu and CD3. Ertumaxomab activates Fcγ type I/III-receptors, forming a tri-cell complex among tumour cell, T cell and accessory cell. Ertumaxomab has been used to research breast cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> JAK/STAT Signaling >> EGFR
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

[References]

[1]. Kiewe P, Thiel E. Ertumaxomab: a trifunctional antibody for breast cancer treatment. Expert Opin Investig Drugs. 2008 Oct;17(10):1553-8.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds