Ertumaxomab

Names

[ Name ]:
Ertumaxomab

Biological Activity

[Description]:

Ertumaxomab (Anti-Human CD22 Recombinant Antibody) is a bispecific antibody targeting HER2/neu and CD3. Ertumaxomab activates Fcγ type I/III-receptors, forming a tri-cell complex among tumour cell, T cell and accessory cell. Ertumaxomab has been used to research breast cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> EGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

[References]

[1]. Kiewe P, Thiel E. Ertumaxomab: a trifunctional antibody for breast cancer treatment. Expert Opin Investig Drugs. 2008 Oct;17(10):1553-8.

Chemical & Physical Properties

No Any Chemical & Physical Properties