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Mocravimod

Names

[ CAS No. ]:
509092-16-4

[ Name ]:
Mocravimod

[Synonym ]:
KNF-299
2-amino-2-[4-(benzyloxyphenylthio)-2-chlorophenyl]ethyl-1,3-propane-diol
2-amino-2-{2-[4-(3-benzyloxyphenylsulfanyl)-2-chlorophenyl]ethyl}propane-1,3-diol
2-amino-2-{2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]-ethyl}propan-1,3-diol
2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl]-1,3-propanediol
2-amino-2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl-1,3-propanediol

Biological Activity

[Description]:

Mocravimod is an oral activity amphematoshenol-1-1-phosphate receptor (S1PR) regulator, which can block the required signal from lymph organs to prevent the migration of effect cells from migrating to non-lymph hematopoietic tissue. Mocravimod can be used for cancer research[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> LPL Receptor

[References]

[1]. Simone Dertschnig, et al. Mocravimod, a Selective Sphingosine-1-Phosphate Receptor Modulator, in Allogeneic Hematopoietic Stem Cell Transplantation for Malignancy. Transplant Cell Ther. 2023 Jan;29(1):41.e1-41.e9.   

Chemical & Physical Properties

[ Molecular Formula ]:
C24H26ClNO3S

[ Molecular Weight ]:
443.98600

[ Exact Mass ]:
443.13200

[ PSA ]:
101.01000

[ LogP ]:
5.38520

Related Compounds