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5-FAM-Alkyne

Names

[ CAS No. ]:
510758-19-7

[ Name ]:
5-FAM-Alkyne

[Synonym ]:
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxamide, 3',6'-dihydroxy-3-oxo-N-2-propyn-1-yl-
3',6'-Dihydroxy-3-oxo-N-(2-propyn-1-yl)-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxamide

Biological Activity

[Description]:

5-FAM-Alkyne is a high selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP)[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
Research Areas >> Others

[In Vitro]

One piece containing FAM fluorophore can easily diffuse into solution and give off a strong fluorescence signal[1].

[References]

[1]. Mengmeng Zhao, et al. A Sensitive Fluorescence Biosensor for Alkaline Phosphatase Activity Based on the Cu(II)-dependent DNAzyme. Anal Chim Acta. 2016 Dec 15;948:98-103.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
709.6±60.0 °C at 760 mmHg

[ Melting Point ]:
313 °C(dec.)

[ Molecular Formula ]:
C24H15NO6

[ Molecular Weight ]:
413.379

[ Flash Point ]:
382.9±32.9 °C

[ Exact Mass ]:
413.089935

[ LogP ]:
2.00

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.767

Related Compounds