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GP 1A

Names

[ CAS No. ]:
511532-96-0

[ Name ]:
GP 1A

[Synonym ]:
1-(2,4-Dichlorophenyl)-6-methyl-N-(1-piperidinyl)-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide
Indeno[1,2-c]pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-1,4-dihydro-6-methyl-N-1-piperidinyl-
1-(2,4-dichlorophenyl)-6-methyl-N-(1-piperidinyl)-4H-indeno[1,2-c]pyrazole-3-carboxamide
1-(2,4-Dichlorophenyl)-6-methyl-N-(piperidin-1-yl)-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide

Biological Activity

[Description]:

GP1a is a potent agonist of cannabinoid receptor 2 (CB2). Gp1a is beneficial to skin wound healing. GP1a inhibits inflammation and fibrogenesis while promoting re-epithelialization[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease
Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor

[References]

[1]. Zhao C, et al. An enzyme-responsive Gp1a-hydrogel for skin wound healing. J Biomater Appl. 2021;36(4):714-721.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C23H22Cl2N4O

[ Molecular Weight ]:
441.353

[ Exact Mass ]:
440.117065

[ LogP ]:
5.23

[ Index of Refraction ]:
1.711

Related Compounds