Canthaxanthin
Names
[ CAS No. ]:
514-78-3
[ Name ]:
Canthaxanthin
[Synonym ]:
MFCD00016364
β,β-Carotene-4,4'-dione, (7cis,9cis,11cis,13cis)-
(7cis,9cis,11cis,13cis)-β,β-Carotene-4,4'-dione
Canthaxanthin
all-trans-Canthaxanthin
EINECS 208-187-2
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[In Vivo]
[Animal admin]
[References]
[1]. Esatbeyoglu T, et al. Canthaxanthin: From molecule to function. Mol Nutr Food Res. 2017 Jun;61(6).
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
717.0±40.0 °C at 760 mmHg
[ Molecular Formula ]:
C40H52O2
[ Molecular Weight ]:
564.840
[ Flash Point ]:
253.9±24.3 °C
[ Exact Mass ]:
564.396729
[ PSA ]:
34.14000
[ LogP ]:
10.69
[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C
[ Index of Refraction ]:
1.575
[ Storage condition ]:
0-6°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FI0330000
- CHEMICAL NAME :
- beta-Carotene-4,4'-dione, all-trans-
- CAS REGISTRY NUMBER :
- 514-78-3
- BEILSTEIN REFERENCE NO. :
- 1898520
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C40-H52-O2
- MOLECULAR WEIGHT :
- 564.92
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 86 mg/kg/15W-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - retinal changes (pigmentary depositions, retinitis, other)
- REFERENCE :
- MJAUAJ Medical Journal of Australia. (Australasian Medical Pub. Co. Ltd., 71-79 Arundel St., Glebe, N.S.W., Australia) V.1- 1914- Volume(issue)/page/year: 143,622,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 47,39,1979
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Risk Phrases ]:
25-36/37/38
[ Safety Phrases ]:
45-36/37/39-28A-26
[ RIDADR ]:
UN 2811 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
GA0875000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
3204199000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 3204199000
Articles
Int. J. Biol. Macromol. 51(4) , 618-26, (2012)
An acceptable strategy to incorporate canthaxanthin (CX) as a natural colorant into products is by means of oil-in-water emulsions. The used CX in this study was produced by bacterium Dietzia natronol...
Influence of canthaxanthin on broiler breeder reproduction, chick quality, and performance.Poult. Sci. 90(7) , 1516-22, (2011)
To investigate the effect of canthaxanthin supplied via a maternal route on the production of both breeder hens and chickens, 270 Chinese Three-Yellow breeder hens were randomly divided into 2 groups ...
Determination of supplemental feeding needs for astaxanthin and canthaxanthin in salmonids by supramolecular solvent-based microextraction and liquid chromatography-UV/VIS spectroscopy.Food Chem. 134(2) , 1244-9, (2012)
Development of simple and rapid analytical methods for predicting supplemental feeding requirements in aquaculture is a need to reduce production costs. In this article, a supramolecular solvent (SUPR...