cis-(Z)-Flupentixol dihydrochloride
Names
[ CAS No. ]:
51529-01-2
[ Name ]:
cis-(Z)-Flupentixol dihydrochloride
[Synonym ]:
1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)thioxanthen-9-ylidene)propyl)-, dihydrochloride (8CI)
(Z)-4-(3-(2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-1-piperazineethanol dihydrochloride
1-Piperazineethanol, 4-[3-[2- (trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, dihydrochloride
cis-Flupentixol Hydrochloride
FUPENTIXOL DIHYDROCHLORIDE
FLUPENTIXOL DIHYDROCHLORIDE
4-[3-[(3Z)-2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol Hydrochloride
a-Flupenthixol Hydrochloride
Zimelidine dihydrochloride
Fupentixol HCl
4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride
(Z)-4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride
2-(4-{(3E)-3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}-1-piperazinyl)ethanol dihydrochloride
2-(4-{(3E)-3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethanol dihydrochloride
Metamin
1-Piperazineethanol, 4-[(3E)-3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, hydrochloride (1:2)
Thioxanthene, 9-(3-(4-(2-hydroxyethyl)piperazinyl)propylidene)-2-trifluoromethyl-, dihydrochloride
Fluanxol dihydrochloride
1-Piperazineethanol, 4-[(3Z)-3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, hydrochloride (1:2)
2-(4-{(3Z)-3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}-1-piperazinyl)ethanol dihydrochloride
1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-, dihydrochloride (9CI)
CIS-(Z)-FLUPENTHIXOL DIHYDROCHLORIDE ANT IPSYCHOTIC,NEUROL
1-Piperazineethanol, 4-[3-[2- (trifluoromethyl)thioxanthen-9-ylidene]propyl]-, dihydrochloride
2-(4-{(3Z)-3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethanol dihydrochloride
flupentixolhydrochloride
fx703
cis-(Z)-Flupentixol Dihydrochloride
Biological Activity
[Description]:
[Related Catalog]:
[Target]
D2 Receptor:0.38 nM (Ki)
5-HT2A Receptor:7 nM (Ki)
[In Vivo]
[References]
Chemical & Physical Properties
[ Boiling Point ]:
554.7ºC at 760 mmHg
[ Melting Point ]:
194-202ºC
[ Molecular Formula ]:
C23H27Cl2F3N2OS
[ Molecular Weight ]:
507.440
[ Flash Point ]:
289.3ºC
[ Exact Mass ]:
506.117310
[ PSA ]:
52.01000
[ LogP ]:
6.08150
[ Appearance of Characters ]:
white to off-white
[ Storage condition ]:
-20°C Freezer
[ Water Solubility ]:
H2O: soluble
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312 + H332
[ Precautionary Statements ]:
P261-P280-P301 + P312 + P330
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
S36/37/39
[ RIDADR ]:
UN 2811
[ RTECS ]:
TL9900000
[ HS Code ]:
2942000000
Customs
[ HS Code ]: 2942000000
Articles
PLoS Negl. Trop. Dis. 9(3) , e0003515, (2015)
New mode-of-action insecticides are sought to provide continued control of pesticide resistant arthropod vectors of neglected tropical diseases (NTDs). We previously identified antagonists of the AaDO...
The nucleus accumbens shell and the dorsolateral striatum mediate the reinforcing effects of cocaine through a serial connection.Behav. Pharmacol. 26(1-2) , 193-9, (2014)
The reinforcing and addictive properties of cocaine are thought to rely on the dopaminergic innervation of the striatum. The ventromedial [i.e. nucleus accumbens shell (NAcc) shell] and dorsolateral [...
A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.Sci. Transl. Med. 7 , 290ra89, (2015)
Currently, no approved therapeutics exist to treat or prevent infections induced by Ebola viruses, and recent events have demonstrated an urgent need for rapid discovery of new treatments. Repurposing...