Phosphodiesterase-IN-1

Names

[ Name ]:
Phosphodiesterase-IN-1

Biological Activity

[Description]:

Phosphodiesterase-IN-1 (Compound 7) is a phosphodiesterase (PDE) inhibitor with anti-Plasmodium activity. Phosphodiesterase-IN-1 has antiproliferative activity against P. falciparum (strain 3D7) with an IC50 value of 0.64 μM[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

Research Areas >> Infection

[References]

[1]. Howard BL, et al. Identification of potent phosphodiesterase inhibitors that demonstrate cyclic nucleotide-dependent functions in apicomplexan parasites. ACS Chem Biol. 2015 Apr 17;10(4):1145-54.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₅FN₄O

[ Molecular Weight ]:
286.30