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allo-yohimbine

Names

[ CAS No. ]:
522-94-1

[ Name ]:
allo-yohimbine

[Synonym ]:
Methyl (16α,17α,20α)-17-hydroxyyohimban-16-carboxylate

Biological Activity

[Description]:

Alloyohimbine, an alkaloid, is a selective α2-adrenoceptor antagonist with K Dα1, K Dα2 of 0.28 μM and 0.006 μM, respectively[1].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

[References]

[1]. N Ferry, et al. Binding of yohimbine stereoisomers to alpha-adrenoceptors in rat liver and human platelets. Br J Pharmacol. 1983 Feb;78(2):359-64.  

Chemical & Physical Properties

[ Density]:
1.31g/cm3

[ Boiling Point ]:
543ºC at 760mmHg

[ Melting Point ]:
104 °C

[ Molecular Formula ]:
C21H26N2O3

[ Molecular Weight ]:
354.44300

[ Flash Point ]:
282.2ºC

[ Exact Mass ]:
354.19400

[ PSA ]:
65.56000

[ LogP ]:
2.58500

[ Index of Refraction ]:
1.66


Related Compounds