Glucametacine

Names

[ CAS No. ]:
52443-21-7

[ Name ]:
Glucametacine

[Synonym ]:
Glucametacina [INN-Spanish]
Glucametacin
Teoremac
Glucometacin
Glucametacine
Glucametacine [INN-French]
UNII-N1EXE5EHAN
Glucametacin [INN]
Glucametacinum [INN-Latin]
EINECS 257-923-9

Biological Activity

[Description]:

Glucametacine is an anti-inflammatory agent[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Guimarães SA, Assessment of the antiexudative and antiproliferative activities of non-steroidal anti-inflammatory drugs in inflammatory models developed in rats by subcutaneous implantation of bacterial cell walls from the dental plaque. Inflammation. 1996 Dec;20(6):623-36.

Chemical & Physical Properties

[ Density]:
1.44

[ Boiling Point ]:
793.7ºC at 760mmHg

[ Molecular Formula ]:
C25H27ClN2O8

[ Molecular Weight ]:
518.94

[ Flash Point ]:
433.8ºC

[ Exact Mass ]:
536.15600

[ PSA ]:
159.71000

[ LogP ]:
1.08540

[ Index of Refraction ]:
1.634

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ6775000
CHEMICAL NAME :
D-Glucose, 2-(((1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol- 3-yl)acetyl)amino)-2- deoxy-, hydrate
CAS REGISTRY NUMBER :
52443-21-7
LAST UPDATED :
198910
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C25-H27-Cl-N2-O8.H2-O
MOLECULAR WEIGHT :
537.01

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
84 mg/kg/14D-I
TOXIC EFFECTS :
Behavioral - headache Gastrointestinal - other changes
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,435,1975

Related Compounds