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6-Thioinosine Phosphate

Names

[ CAS No. ]:
53-83-8

[ Name ]:
6-Thioinosine Phosphate

[Synonym ]:
thioinosinic acid
6-Thio-IMP
6-thioinosine 5'-monophosphate
6-Thio-5'-inosinic Acid
6-Thioinosinic Acid
6-Thio
6-Mercaptopurine Ribonucleotide
6-Thioinosine 5'-Phosphate

Biological Activity

[Description]:

6-Thioinosine Phosphate (Thioinosinic acid) is an intermediate metabolite of azathioprine (HY-B0256). Azathioprine is a purine analog immunosuppressive drug[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Fletcher L, et al. Assay of thioinosinic acid, an active metabolite of azathioprine, in human lymphocytes. Br J Clin Pharmacol. 1980 Sep;10(3):287-92.  

Chemical & Physical Properties

[ Density]:
2.25g/cm3

[ Boiling Point ]:
833.4ºC at 760mmHg

[ Melting Point ]:
149-155ºC (dec.)

[ Molecular Formula ]:
C10H13N4O7PS

[ Molecular Weight ]:
364.27

[ Flash Point ]:
457.9ºC

[ Exact Mass ]:
364.02400

[ PSA ]:
208.66000

[ Index of Refraction ]:
1.903

Related Compounds