Deacetylnorgestimate

Names

[ Name ]:
Deacetylnorgestimate

[Synonym ]:
UNII-R0TAY3X631
Levonorgestrel oxime
17-Desacetyl Norgestimate
Norplant 3-oxime
17-deacetylated norgestimate
Norelgestromin
(17alpha)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one oxime (E)- and
D-Norgestrel 3-oxime
17-Deacetylnorgestimate
18-Methylnorethindrone oxime
Deacetylnorgestimate
Norgestimate metabolite Norelgestromin

Biological Activity

[Description]:

Norelgestromin is a metabolite of Norgestimate, which is a progestin or synthetic progestogen.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.23g/cm3

[ Boiling Point ]:
491.9ºC at 760mmHg

[ Melting Point ]:
107-109ºC

[ Molecular Formula ]:
C₂₁H₂₉NO₂

[ Molecular Weight ]:
327.46000

[ Flash Point ]:
327.1ºC

[ Exact Mass ]:
327.22000

[ PSA ]:
52.82000

[ LogP ]:
4.14370

[ Index of Refraction ]:
1.633

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JF8309000

CHEMICAL NAME :: 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, oxime, (8-alpha,9-beta,10-alpha,13- alpha,14-beta)-

CAS REGISTRY NUMBER :: 53016-31-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H29-N-O2

MOLECULAR WEIGHT :: 327.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 20 mg/kg

SEX/DURATION :: female 1-4 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

REFERENCE :: YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 23,252,1988

Safety Information

[ RIDADR ]:
NONH for all modes of transport