TMB-8

Names

[ Name ]:
TMB-8

[Synonym ]:
MFCD00012502
8-(Diethylamino)octyl 3,4,5-trimethoxybenzoate hydrochloride
8-(diethylamino)octyl 3,4,5-trimethoxybenzoate,hydrochloride
EINECS 258-574-5

Biological Activity

[Description]:

TMB-8 is a novel Ca 2+ antagonist. TMB-8 may exert inhibitory effects in smooth muscle by blocking Ca 2+ release from intracellular bound stores.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Neurological Disease

[References]

[1]. Malagodi MH, et al. Pharmacological evaluation of a new Ca2+ antagonist, 8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8): studies in smooth muscles. Eur J Pharmacol. 1974 Jun;27(1):25-33.

Chemical & Physical Properties

[ Density]:
1.018g/cm3

[ Boiling Point ]:
461.2ºC at 760mmHg

[ Melting Point ]:
94-97 °C(lit.)

[ Molecular Formula ]:
C₂₂H₃₈ClNO₅

[ Molecular Weight ]:
431.99

[ Flash Point ]:
232.8ºC

[ Exact Mass ]:
431.24400

[ PSA ]:
57.23000

[ LogP ]:
5.35360

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922509090

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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