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Decamethylcyclopentasiloxane

Names

[ CAS No. ]:
541-02-6

[ Name ]:
Decamethylcyclopentasiloxane

[Synonym ]:
MFCD00046966
Cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl-
D5 Cyclomethicone
decamethyl cyclopentasiloxane
Cyclic dimethylsiloxane pentamer
Decamethyl-cyclopentasiloxane
2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
Decamethylcyclopentasiloxane
2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane
EINECS 208-764-9

Biological Activity

[Description]:

Decamethylcyclopentasiloxane (D5), an organosilicon compound that is used as a skin emollient in cosmetics and personal products[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
210.0±0.0 °C at 760 mmHg

[ Melting Point ]:
-44°C

[ Molecular Formula ]:
C10H30O5Si5

[ Molecular Weight ]:
370.770

[ Flash Point ]:
95.6±23.0 °C

[ Exact Mass ]:
370.093964

[ PSA ]:
46.15000

[ LogP ]:
3.59200

[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.427

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GY5945200
CHEMICAL NAME :
Cyclopentasiloxane, decamethyl-
CAS REGISTRY NUMBER :
541-02-6
BEILSTEIN REFERENCE NO. :
1800166
LAST UPDATED :
199710
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C10-H30-O5-Si5
MOLECULAR WEIGHT :
370.85

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1234,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1234,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>64 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 28,313,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>16 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 28,313,1974 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3060 mg/m3/6H/4W-I
TOXIC EFFECTS :
Liver - changes in liver weight Blood - other changes Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 15,181,1995

Safety Information

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
GY5945200

[ HS Code ]:
29310095

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2931900001

[ Summary ]:
2931900001 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:6.5%。General tariff:30.0%

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