2-Methylthioethyl chloride

Names

[ CAS No. ]:
542-81-4

[ Name ]:
2-Methylthioethyl chloride

[Synonym ]:
β-Chloroethyl methyl sulfide
MFCD00000978
1-Chloro-2-(methylsulfanyl)ethane
Ethane, 1-chloro-2- (methylthio)-
2-Chloroethyl Methyl Sulfide
2-Methylthioethyl chloride
1-chloro-2-(methylthio)ethane
Sulfide, 2-chloroethyl methyl (8CI)
EINECS 208-828-6
Ethane, 1-chloro-2-(methylthio)-

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
140.0±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃H₇ClS

[ Molecular Weight ]:
110.606

[ Flash Point ]:
42.2±0.0 °C

[ Exact Mass ]:
109.995697

[ PSA ]:
25.30000

[ LogP ]:
1.43

[ Vapour Pressure ]:
7.8±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.469

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H302-H311 + H331-H314-H350

[ Precautionary Statements ]:
P201-P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
S26-S45-S36-S37-S39

[ RIDADR ]:
UN 2924 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

[ HS Code ]:
2930909090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

2,6-Dithiopurine blocks toxicity and mutagenesis in human skin cells exposed to sulfur mustard analogues, 2-chloroethyl ethyl sulfide and 2-chloroethyl methyl sulfide.

Chem. Res. Toxicol. 23(3) , 497-503, (2010)

Sulfur mustard (bis-(2-chloroethyl)sulfide) is a well-known chemical warfare agent that induces debilitating cutaneous toxicity in exposed individuals. It is also known to be carcinogenic and mutageni...

The more basic isoform of eEF1A relates to tumour cell phenotype and is modulated by hyper-proliferative/differentiating stimuli in normal lymphocytes and CCRF-CEM T-lymphoblasts.

Hematol. Oncol. 31(2) , 370-6, (2013)

The elongation factor 1A proteins (eEF1A1/A2) are known to play a role in tumours. We previously found that a more basic isoform of eEF1A (MBI-eEF1A) is present in the cytoskeletal/nuclear-enriched ex...

Cutaneous toxicity of 2-chloroethyl methyl sulfide in isolated perfused porcine skin.

Toxicol. Appl. Pharmacol. 104(1) , 167-79, (1990)

Previous research has shown the isolated perfused porcine skin flap (IPPSF) to be a novel in vitro experimental model for investigating xenobiotic percutaneous absorption. In this study, the IPPSF was...