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(+)-Fluprostenol

Names

[ CAS No. ]:
54276-17-4

[ Name ]:
(+)-Fluprostenol

[Synonym ]:
5-Heptenoic acid, 7-[3,5-dihydroxy-2-[(1E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, (5E)-
(+)-FLUPROSTENOL
(5E)-7-(3,5-Dihydroxy-2-{(1E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}cyclopentyl)-5-heptenoic acid
Travoprost Acid
Fluprostenol

Biological Activity

[Description]:

(+)-Fluprostenol is a potent agonist of PTGER2. (+)-Fluprostenol decreases the expression of Oviductal glycoprotein 1 (OVGP1)[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[Target]

PTGER2[1]


[References]

[1]. Zhang N, et al. The prostaglandin E2 receptor PTGER2 and prostaglandin F2α receptor PTGFR mediate oviductal glycoprotein 1 expression in bovine oviductal epithelial cells. J Reprod Dev. 2018;64(2):101-108.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
608.0±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H29F3O6

[ Molecular Weight ]:
458.468

[ Flash Point ]:
321.5±31.5 °C

[ Exact Mass ]:
458.191620

[ PSA ]:
107.22000

[ LogP ]:
2.55

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.575

Safety Information

[ RIDADR ]:
UN 1992 6.1(3) / PGII

Related Compounds