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NSC 745887

Names

[ CAS No. ]:
54490-26-5

[ Name ]:
NSC 745887

[Synonym ]:
naphtho<2,3-f>quinoxaline-7,12-dione
naphtho[2,3-f]quinoxaline-7,12-dione
1,4-Diaza-benzo[a]anthracene-7,12-dione
Naphtho<2,3-f>chinoxalin-7,12-dion
7,12-dioxo-7,12-dihydroanthra[1,2-b]pyrazine

Biological Activity

[Description]:

NSC745887 (compound 25) is an anti-cancer agent. NSC745887 exhibits dose-dependent inhibition of proliferation in all 60 cancer cell lines[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Huang HS, et al. Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,11-dione homologues. Bioorg Med Chem. 2009;17(21):7418-7428.

Chemical & Physical Properties

[ Density]:
1.448±0.06 g/cm3(Predicted)

[ Boiling Point ]:
491.6±40.0 °C(Predicted)

[ Molecular Formula ]:
C16H8N2O2

[ Molecular Weight ]:
260.25

[ Exact Mass ]:
260.05900

[ PSA ]:
59.92000

[ LogP ]:
2.40520

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds