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Methyl protogracillin

Names

[ CAS No. ]:
54522-53-1

[ Name ]:
Methyl protogracillin

[Synonym ]:
β-D-arabino-Hexopyranoside, (3β,22β,25R)-26-(β-D-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->3)]-, (2ξ)-
(3β,22R,25R)-26-(β-D-Glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->3)]-(2ξ)-β-D-arabino-hexopyranoside

Biological Activity

[Description]:

Methyl protogracillin (NSC-698793), isolated from the roots of Dioscorea opposite Thunb, exhibits strong anti-cancer activity[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Hu K, et al. The cytotoxicity of methyl protoneogracillin (NSC-698793) and gracillin (NSC-698787), two steroidal saponins from the rhizomes of Dioscorea collettii var. hypoglauca, against human cancer cells in vitro. Phytother Res. 2003 Jun;17(6):620-6.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C52H86O23

[ Molecular Weight ]:
1079.225

[ Exact Mass ]:
1078.556030

[ LogP ]:
1.34

[ Index of Refraction ]:
1.628

[ Water Solubility ]:
Insuluble (3.2E-3 g/L) (25 ºC)

Related Compounds