lucPpy-IN-1

Names

[ Name ]:
lucPpy-IN-1

[Synonym ]:
Methanone, [2-(4-methylphenyl)-4-quinolinyl][4-(2-pyrimidinyl)-1-piperazinyl]-

Biological Activity

[Description]:

lucPpy-IN-1 (compound 9) is an ATP-dependent luciferase from Photinus pyralis (lucPpy) inhibitor with an IC50 value of 4.0 µM. lucPpy-IN-1 can be used for the research of target’s druggability[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[Target]

IC50: 4.0 µM (lucPpy)[1]

[In Vitro]

lucPpy-IN-1 (0.1 nM-100 µM) inhibits activity of lucPpy with an IC50 value of 4.0 µM[1].

[References]

[1]. Auld DS, et al. A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution. J Med Chem. 2009 Mar 12;52(5):1450-8.

Chemical & Physical Properties

[ Density]:
1.410±0.06 g/cm3(Predicted)

[ Boiling Point ]:
312.4±37.0 °C(Predicted)

[ Molecular Formula ]:
C₂₅H₂₃N₅O

[ Molecular Weight ]:
409.48

lucPpy-IN-1

Names

Biological Activity

Chemical & Physical Properties

Related Compounds