<Suppliers Price>

Sempervirine

Names

[ CAS No. ]:
549-92-8

[ Name ]:
Sempervirine

[Synonym ]:
sempervirine
yohimba-2,5,14,20-tetraene
Sempervirin

Biological Activity

[Description]:

Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Noriyuki Kogure, et al. Total synthesis and full NMR assignment of ourouparine, a yohimbane-type indole alkaloid isolated from Gelsemium sempervirens. Journal of Natural Medicines volume 

Chemical & Physical Properties

[ Density]:
1.28g/cm3

[ Boiling Point ]:
591.6ºC at 760mmHg

[ Melting Point ]:
271ºC

[ Molecular Formula ]:
C19H16N2

[ Molecular Weight ]:
331.32500

[ Flash Point ]:
311.6ºC

[ Exact Mass ]:
331.09600

[ PSA ]:
88.77000

[ LogP ]:
4.49710

Safety Information

[ Risk Phrases ]:
23/24/25

[ Safety Phrases ]:
22-36/37/39

Related Compounds