Tiliquinol

Names

[ Name ]:
Tiliquinol

[Synonym ]:
5-methylquinolin-8-ol
5-methyl-8-hydroxyquinoline
Tiliquinol [INN]
Tiliquinol
5-Methyl-8-quinolinol
8-Quinolinol, 5-methyl-

Biological Activity

[Description]:

Tiliquinol (NSC 130828) is a non-absorbed anti-amoebic luminal agent. Tiliquinol is used in combination with tibroquinol. Tiliquinol can be used for the research of amebic liver abscess[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Nespola B, et al. First case of amebic liver abscess 22 years after the first occurrence. Parasite. 2015;22:20.

[2]. Desoubeaux G, et al. Unusual multiple large abscesses of the liver: interest of the radiological features and the real-time PCR to distinguish between bacterial and amebic etiologies. Pathog Glob Health. 2014;108(1):53-57.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
324.7±22.0 °C at 760 mmHg

[ Melting Point ]:
122-124°C

[ Molecular Formula ]:
C₁₀H₉NO

[ Molecular Weight ]:
159.185

[ Flash Point ]:
150.2±22.3 °C

[ Exact Mass ]:
159.068420

[ PSA ]:
33.12000

[ LogP ]:
2.33

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.666

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%