Methyl serinate hydrochloride

Names

[ Name ]:
Methyl serinate hydrochloride

[Synonym ]:
methyl DL-serinate hydrochloride
Q1YZVO1 &&HCl
EINECS 227-047-1
Isoquinoline, 1,2,3,4-tetrahydro-1-methyl-
Methyl-DL-serine hydrochloride
Serine, methyl ester, hydrochloride (1:1)
1-Methyl-1,2,3,4-tetrahydroisoquinoline
Methyl serinate hydrochloride
MFCD00012593
Methyl serinate hydrochloride (1:1)
DL-serine methylester Hydrochloride
1,2,3,4-Tetrahydro-1-methylisoquinoline 1MeTIQ

Biological Activity

[Description]:

H-DL-Ser-OMe.HCl is a serine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
239.3±9.0 °C at 760 mmHg

[ Melting Point ]:
134-136 °C(lit.)

[ Molecular Formula ]:
C₁₀H₁₃N

[ Molecular Weight ]:
147.217

[ Flash Point ]:
100.0±14.2 °C

[ Exact Mass ]:
147.104797

[ PSA ]:
69.56000

[ LogP ]:
1.90

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.522

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29225000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Acylated serine derivatives: a unique class of arthropod pheromones of the Australian redback spider, Latrodectus hasselti.

Angew. Chem. Int. Ed. Engl. 49(11) , 2037-40, (2010)

The novel and efficient direct synthesis of N,O-acetal compounds using a hypervalent iodine(III) reagent: an improved synthetic method for a key intermediate of discorhabdins.

Chem. Commun. (Camb.) (13) , 1764-6, (2005)

The use of hypervalent iodine(III) reagents allowed us to develop the novel and efficient direct synthesis of N,O-acetal compounds via the oxidative fragmentation reaction of alpha-amino acids or alph...

Aziridinium from N,N-dibenzyl serine methyl ester: synthesis of enantiomerically pure beta-amino and alpha,beta-diamino esters.

Org. Lett. 8(10) , 2183-6, (2006)

[reaction: see text] Reaction of N,N-dibenzyl-O-methylsulfonyl serine methyl ester with a variety of heteronucleophiles (sodium azide, sodium phthalimide, amines, thiols) and carbanions (sodium malona...