(4S)-4-amino-4-[[(1S)-4-amino-1-carboxy-butyl]carbamoyl]butanoic acid

Names

[ Name ]:
(4S)-4-amino-4-[[(1S)-4-amino-1-carboxy-butyl]carbamoyl]butanoic acid

[Synonym ]:
γ glutamyl ornithine
L-α-Glutamyl-L-ornithine
L-Ornithine, L-α-glutamyl-

Biological Activity

[Description]:

γ-Glutamylornithine is the urine excreta of patients with HHH syndrome (hyperuricemia, hyperaminemia, and hypercitrullinuria) and rotary atrophy associated with hyperuricemia. Increased levels of endogenous ornithine increase levels of γ-Glutamylornithine in the urine[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Roesel R A, et al. γ-Glutamylornithine excretion in patients with hyperornithinemia[J]. Clinica chimica acta, 1984, 140(2): 133-138.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
613.7±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₉N₃O₅

[ Molecular Weight ]:
261.275

[ Flash Point ]:
324.9±31.5 °C

[ Exact Mass ]:
261.132477

[ LogP ]:
-1.55

[ Vapour Pressure ]:
0.0±3.8 mmHg at 25°C

[ Index of Refraction ]:
1.544