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efrotomycin

Names

[ CAS No. ]:
56592-32-6

[ Name ]:
efrotomycin

[Synonym ]:
Antibiotic FR 02A
Producil
FR 02A
efrotomycin
MK-621

Biological Activity

[Description]:

Efrotomycin is an orally active antibiotic. Efrotomycin can be isolated from the Streptomyces Lactamdurans. Efrotomycin has insignificant effect on Salmonella typhimurium quantity, duration, shedding rate, and antimicrobial susceptibility in infected pigs[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vivo]

Efrotomycin (16 mg/kg; 口服，加在饲料中; 共 56 天) 处理鼠伤寒沙门菌感染的猪，不影响脱落的菌落在定植后对抗菌药物的敏感性[1]。 Efrotomycin (16 mg/kg; 口服; 共 56 天) 处理的猪，在饲料消耗、体重增加或饲料效率方面没有明显差异[1]。

[References]

[1]. Wax R, et al. Efrotomycin, a new antibiotic from Streptomyces lactamdurans. J Antibiot (Tokyo). 1976 Jun;29(6):670-3.  

[2]. Jacks TM, et al. Effect of efrotomycin in feed on the quantity, duration, and prevalence of shedding and antibacterial susceptibility of Salmonella typhimurium in experimentally infected swine. Am J Vet Res. 1988 Nov;49(11):1832-5.  

Chemical & Physical Properties

[ Molecular Formula ]:
C59H88N2O20

[ Molecular Weight ]:
1145.33000

[ Exact Mass ]:
1144.59000

[ PSA ]:
303.88000

[ LogP ]:
3.60900

[ Index of Refraction ]:
1.574

Related Compounds